Osteogenesis Imperfecta Tarda. A Review with Case Reports

S. |NIYOGI, m.b. (Cal.) Surgical Registrar,"Nilratan Sarkar Medical College Hospitals, Calcutta Osteogenesis imperfecta tarda is one variety a clinical syndrome which has been given various names such as fragilitas ossium, idiopathic osteopsathyrosis, periosteal dysplasia, etc. Thomson (1921) divided it into two broad clinical types?preand post-natal. Pre-natal cases are more severe and often the babies are stillborn with innumerable fractures. Knaggs .?924) described four types : (a) foetal, (?>) infantile, (c) adolescent or osteogenesis imperfecta tarda, and (d) adult type. Fairbank (1930, 1935, 1948), who is an authority on the subject, modified Knaggs' classification and described the following varieties : (1) Type 1.?Thick bone type, usually severe Pre-natal cases, born with thick achondroplasic bones. Usually the proximal segments of the hmb bones such as the humerus and the femur are involved. These babies scarcely live for niore than 3 months.